It's over for Charlie Sheen.

After a day of unhinged and unsolicited comments ripping his show's executive producer Chuck Lorre and assorted enemies -- Alcoholics Anonymous and Thomas Jefferson, among others -- the star finally went further than CBS and Warner Brothers Television could take.

The network and TV production company announced Thursday that they had pulled the plug on television's top-rated comedy, "Two and a Half Men," which was scheduled to restart production on Monday.

"Based on the totality of Charlie Sheen's statements, conduct and condition, CBS and Warner Bros. Television have decided to discontinue production of "Two and a Half Men" for the remainder of the season," the companies said in a joint statement.

A spokesman for Sheen -- not that he appears to be relying on one these days -- had no immediate comment.

The show, which airs on Mondays at 9 pm and has been on hiatus since Jan. 28, has shot 16 of 24 episodes this season. The final eight will apparently not be shot.

To replace "Two and a Half Men," CBS has ordered more episodes of "Mike and Molly," another Lorre-produced show, and "Rules of Engagement."

But even with Sheen's public misbehavior, his show has been performing in the ratings, remaining the most-watched comedy on TV.

Needless to say, Sheen does not appear to be following a rehabilitation program that he'd supposedly committed to in the past few weeks.

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